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Publication : A new allele at the Mup-1 locus controlling an electrophoretic variant of major urinary proteins in mice.

First Author  Nikaido H Year  1984
Journal  J Hered Volume  75
Issue  1 Pages  59-61
PubMed ID  6707444 Mgi Jnum  J:7386
Mgi Id  MGI:55857 Doi  10.1093/oxfordjournals.jhered.a109866
Citation  Nikaido H, et al. (1984) A new allele at the Mup-1 locus controlling an electrophoretic variant of major urinary proteins in mice. J Hered 75(1):59-61
abstractText  The present study showed that the presence or absence of a new component of major urinary proteins (Mups), which is found in MOA mice, an inbred strain of Mus musculus molossinus (Japanese wild mice), is controlled by a single codominant gene locus. The linkage analysis shows that the locus is on chromosome 4, where the Mup-1 locus is assigned; its alleles, Mup-1a, and Mup-1b determine two phenotypic forms of MUPs in laboratory mice (M. m. domesticus). Recombination values between the locus and other loci on chromosome 4, such as brown (b), Pgm-2, and Gpd-1 are compatible with the gene order, Mup-1-b-Pgm-2-Gpd-1, on chromosome 4. Thus, it is concluded that the locus is identical to Mup-1 and it is proposed that Mup-1c be designated as the allele that determines a third phenotypic form of MUPs in MOA mice.
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