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Allele : Cd74<em1Hrtn> CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); endonuclease-mediated mutation 1, Cole Harrington

Primary Identifier  MGI:7666006 Allele Type  Endonuclease-mediated
Attribute String  Reporter Gene  Cd74
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technology, a P2A self-cleaving peptide sequence, a red fluorescent protein (tdTomato) sequence, and woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) followed by a polyadenylation signal were inserted to replace the stop codon of the endogenous CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Cd74) gene.
  • mutations:
  • Insertion
  • synonyms:
  • Cd74<tdT>,
  • Cd74<tdT>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele