Primary Identifier | MGI:7666512 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region, Null/knockout | Gene | Del(13Rr492-Rr493)1Andg |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A section of genomic sequence, containing Pitx1 distal or pituitary gland enhancer PDE or Pit, Pitx1 enhancer RA4, the Macroh2a1 gene and Pitx1 pan-limb enhancer Pen, was deleted using sgRNAs (equivalent to GAAACCGGGAGACGGTGATC and CGTGCTATCGAGGGACTAAT ) with CRISPR/Cas9 technology. |