Primary Identifier | MGI:7703589 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Apoe |
Strain of Origin | B6.Cg-Apoe<em2(APOE*)Adiuj>/J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 genome editing methodologies were used to introduce p.R136S (Christchurch) point mutations in the human APOE (APOE isoform E3) carried by the Apoeem2(APOE*)Adiuj allele which has the p.R130C point mutation in the human APOE protein. |