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Allele : Apoe<em1(APOE*)Msasn> apolipoprotein E; endonuclease-mediated mutation 1, Michael Sasner
Primary Identifier  MGI:7703565 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Apoe
Strain of Origin  B6.Cg-Apoe<em2(APOE*)Adiuj>/J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-Cas9 methodology introduced a Jacksonville V236E (p.V236R) point mutation into the human APOE (APOE isoform E3) protein carried by the Apoeem2(APOE*)Adiuj allele which has the p.R130C point mutation in the human APOE (APOE isoform E3) protein.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele




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