| Primary Identifier | MGI:7703878 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | App |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Using CRISPR/Cas9 technology, the humanizing A(beta) region R684H, F681Y, and G676R mutations, and the KM670/671NL (Swedish) mutation, as well as the I716V (Florida) and V717I (London) mutations were introduced in the mouse App (amyloid beta (A4) precursor protein) gene. |
