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Allele : Tg(tetO-UPF1*R844C)3438Kmke transgene insertion 3438, Kim M Keeling

Primary Identifier  MGI:7787080 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(tetO-UPF1*R844C)3438Kmke
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The dnUPF1 transgene consists of a tetracycline response element (TRE) and minimal CMV promoter, hemagglutinin (HA) epitope tag fused to the N terminus human UPF1 cDNA with an R844C mutation followed by SV40 transcriptional terminator (pA). Two funder lines were generated. This is line 3438 with 12 to 14 copies of transgene which shows higher and broader expression.
  • mutations:
  • Insertion
  • synonyms:
  • dnUPF1,
  • UPF1-R844C,
  • UPF1-R844C,
  • dnUPF1
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele