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Allele : Gt(ROSA)26Sor<tm17(Igk-V/Igh-V)Ics> gene trap ROSA 26, Philippe Soriano; targeted mutation 17, Mouse Clinical Institute
Primary Identifier  MGI:7788438 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
molecularNote  The following elements were inserted into an intron: an adenovirus splice acceptor site, a conditional STOP cassette (loxP site flanked cassette consisting of PGK promoter, neomycin resistance gene, PGK and 3x SV40 p(A) signal sequences), followed by the Igk signal peptide sequence, anti-Otx2 Igk-V/Igh-V single chain variable fragment (scfv) antibody cDNA sequence with 6x Myc- and His-tag sequence in-frame, and bovine GH poly(A) signal sequence. This allele only expresses the antibody after Cre-mediated removal of the stop cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm17(LSL,anti-Otx2)Ics>,
  • scFvOtx2,
  • Gt(ROSA)26Sor<tm17(LSL,anti-Otx2)Ics>,
  • scFvOtx2
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Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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