| Primary Identifier | MGI:7738786 | Allele Type | Endonuclease-mediated |
| Attribute String | Conditional ready, Humanized sequence, Inserted expressed sequence | Gene | Cic |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 20 and a loxP site and exon 20 fused to the C terminal domain of human DUX4 were inserted downstream of the polyA signal vis CRISPR/cas9 mediated recombination. In the absence of cre expression this allele expresses the wild-type protein but after cre-mediated recombination a Cic-DUX4 fusion protein is expressed. |
