Primary Identifier | MGI:7788424 | Allele Type | Targeted |
Attribute String | Conditional ready, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The following elements were inserted into an intron: an adenovirus splice acceptor site, a conditional STOP cassette (loxP site flanked cassette consisting of PGK promoter, neomycin resistance gene, PGK and 3x SV40 p(A) signal sequences), followed by Tnfsf10 cDNA and bovine GH poly(A) signal sequence. This allele only expresses Tnfsf10 after Cre-mediated removal of the stop cassette. |