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Allele : Rr565<em1Timz> regulatory region 565; endonuclease-mediated mutation 1, Tim Zacharewski

Primary Identifier  MGI:7782633 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr565
Is Recombinase  false Is Wild Type  false
molecularNote  The dioxin response element (DRE) in intron 3 of Pkm was targeted using an sgRNA (equivalent to AGGAAGTGGTTATGAAAGCAGGG) and an ssODN template with CRISPR/Cas9 technology, resulting in the deletion of the DRE core sequence GCGTG (GRCm39:chr9:59575386-59575390).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Pkm<deltaDRE>,
  • Pkm<deltaDRE>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele