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Allele : Rr50361<em1Ddu> regulatory region 50361; endonuclease-mediated mutation 1, Denis Duboule

Primary Identifier	MGI:7785479	Allele Type	Endonuclease-mediated
Attribute String	Modified regulatory region	Gene	Rr50361
Is Recombinase	false	Is Wild Type	false

molecularNote

Putative Hoxd enhancer Rr50361, located between Atp5mc3 and Lnpk, was targeted with sgRNAs (equivalent to TCAAATCGTACAGCGCTGCC and CACGGGGTGGAGTTATCTAC) using CRISPR/Cas9 technology, resulting in a 14,269 bp deletion (GRCm39:chr2:74122574-74136842).

mutations:
Intergenic deletion

synonyms:
Del(V),
Del(V)

earliestPublication:
Amandio AR, et al. (2020) A complex regulatory landscape involved in the development of mammalian external genitals. Elife 9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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