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Allele : Rr574<em1Ddu> regulatory region 574; endonuclease-mediated mutation 1, Denis Duboule

Primary Identifier	MGI:7785481	Allele Type	Endonuclease-mediated
Attribute String	Modified regulatory region	Gene	Rr574
Is Recombinase	false	Is Wild Type	false

molecularNote

Putative Hoxd enhancer Rr574, located between Atp5mc3 and Lnpk, was targeted with sgRNAs (equivalent to TAGAATCATTGGTAGTACGG and TGGTTCTAAGATTTCCGTAA) using CRISPR/Cas9 technology, resulting in a 39,050 bp deletion (GRCm39:chr2:74014194-74053243).

mutations:
Intergenic deletion

synonyms:
Del(IIIE),
Del(IIIE)

earliestPublication:
Amandio AR, et al. (2020) A complex regulatory landscape involved in the development of mammalian external genitals. Elife 9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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