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Allele : Pole<em2Ewht> polymerase (DNA directed), epsilon; endonuclease-mediated mutation 2, Eileen White

Primary Identifier  MGI:7797731 Allele Type  Endonuclease-mediated
Gene  Pole Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Using CRISPR technology, a sgRNA (AGGGAATTTGAGAGGCAGTT) was designed to target the Pole gene to introduce CTC to GTT mutations resulting in a leucine acid to valine change at amino acid 424 (L424V).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Pole L424V,
  • Pole L424V
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele