| Primary Identifier | MGI:7856630 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(CD4-Tcrb)1Bnlt |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | cDNAs encoding productively rearranged Vβ4 and Vα4 chains were cloned from a Derp-1-specific hybridoma cell line. The TCRVα and Vβ cDNAs were cloned into human CD4 promoter with silencer and human CD4 promoter expression vectors. These were coinjected to pronuclei of zygotes, but recovered mice express only the rearranged TCRbeta chain. |
