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Allele : Gt(ROSA)26Sor<tm2(TARDBP)Tlbt> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Kevin Talbot
Primary Identifier  MGI:7859507 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (C57BL/6J x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
description  embryonic stem cell line = IDG26.10-3
molecularNote  This allele expresses a single copy of a bacterial artificial chromosome (BAC) construct carrying the entire genomic locus of the human wild-type TARDBP (TDP-43) gene inserted into the mouse endogenous Gt(ROSA)26Sor locus. Human wild-type TDP-43 is expressed at low levels on a background of mouse endogenous TDP-43.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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