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Allele : Rr381<em12Kap> regulatory region 381; endonuclease-mediated mutation 12, Dietmar J. Kappes

Primary Identifier  MGI:7858952 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr381
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  The Zbtb7b silencer, located upstream, was targeted with a dsODN template using TALEN technology (ZFN target sequences (capitalized) ACCGCTACCCTAACCcataaCTGGAAGGGGTTTAG), resulting in the mutation of two EGR (E6, E7) binding sites and one Ebox (T6) motif.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • QW82<->,
  • QW82<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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2 Publication categories

Trail: Allele