Primary Identifier | MGI:7859328 | Allele Type | Endonuclease-mediated |
Attribute String | Conditional ready, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Strain of Origin | 129S9/SvEvH | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The allele carries a MOE (Multi-level Over Expression) allele with coding sequence for MAPT which enables conditional expression via Cre-LoxP excisable stop cassette, switchable promotor via Flp-FRT recombination which removes the stronhger CAG promotor and depends on the lower ROSA 26 promoter expression and WPRE (Woodchuck hepatitis virus posttranscriptional regulatory element) transcript stabilising element excisable via Dre-RoxP recombination . |