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Allele : Gt(ROSA)26Sor<em3(MAPT)H> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 3, Harwell

Primary Identifier  MGI:7859328 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Strain of Origin  129S9/SvEvH Is Recombinase  false
Is Wild Type  false
molecularNote  The allele carries a MOE (Multi-level Over Expression) allele with coding sequence for MAPT which enables conditional expression via Cre-LoxP excisable stop cassette, switchable promotor via Flp-FRT recombination which removes the stronhger CAG promotor and depends on the lower ROSA 26 promoter expression and WPRE (Woodchuck hepatitis virus posttranscriptional regulatory element) transcript stabilising element excisable via Dre-RoxP recombination .
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele