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MP Term : decreased type II pneumocyte number [MP:0010811] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  reduced number of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored
  • synonyms:
  • reduced type 2 alveolocyte number,
  • reduced type 2 pneumocyte number,
  • reduced type II pneumocytes,
  • reduced granular pneumocyte number,
  • decreased TII number,
  • decreased type II alveolocyte number,
  • reduced ATII number,
  • decreased type 2 alveolar epithelial cell number,
  • decreased AT2 number,
  • reduced TII number,
  • reduced AT2 number,
  • decreased type 2 alveolocyte number,
  • decreased type 2 pneumocyte number,
  • reduced Great alveolar cell number,
  • decreased granular pneumocyte number,
  • decreased Cuboidal type II cell number,
  • decreased type II pneumocytes,
  • reduced type II alveolocyte number,
  • decreased type II cell number,
  • decreased type II alveolar epithelial cell number,
  • reduced Lung type II cell number,
  • decreased type II pneumonocyte number,
  • reduced Cuboidal type II cell number,
  • reduced type 2 alveolar epithelial cell number,
  • reduced type II alveolar epithelial cell number,
  • decreased Lung type 2 cell number,
  • reduced type II pneumonocyte number,
  • decreased Great alveolar cell number,
  • reduced Lung type 2 cell number,
  • decreased Lung type II cell number,
  • reduced type II cell number,
  • decreased ATII number
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