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MP Term : abnormal tumor necrosis factor secretion [MP:0008556] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  anomaly in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium
  • synonyms:
  • abnormal cachectin secretion,
  • abnormal tumour necrosis factor secretion,
  • abnormal TNF secretion,
  • abnormal TNFA secretion,
  • abnormal tumor necrosis factor alpha secretion,
  • abnormal tumour necrosis factor alpha secretion
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

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Ontology Term --> Direct parents