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MP Term : abnormal kidney epithelial cell primary cilium physiology [MP:0011744] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  any functional anomaly of the non-motile primary cilia found on renal epithelial cells and thought to act as a mechanical sensor to detect renal tubular fluid; impaired mechanical response of primary cilia to physiological fluid flow, or abnormalities in intracellular Ca2+ increase in response to fluid stress may alter renal (tubular) cell proliferation and differentiation and lead to renal cyst formation
  • synonyms:
  • abnormal renal epithelial cell primary cilia physiology,
  • abnormal renal primary cilium physiology,
  • abnormal renal monocilium physiology,
  • abnormal renal epithelial cell primary cilium physiology,
  • abnormal kidney epithelial cell primary cilia physiology
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

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