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MP Term : abnormal tricarboxylic acid cycle [MP:0010958] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  any anomaly in the universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes; the acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle
  • synonyms:
  • abnormal citric acid cycle,
  • abnormal Krebs cycle,
  • abnormal TCA cycle
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents