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MP Term : abnormal podocyte adhesion [MP:0011864] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  any anomaly in the adhesive properties of glomerular podocytes, resulting in abnormal cell to cell and cell to extracellular matrix (ECM) interactions; podocytes adhere tightly to ECM components of the glomerular basement membrane via an integrin-laminin-actin axis to maintain a functional filtration barrier in the presence of mechanical stress
  • synonyms:
  • abnormal podocyte-ECM adhesion,
  • abnormal podocyte adherence
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents