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MP Term : abnormal blood vessel lumen formation [MP:0020373] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  any anomaly in the process in which a developing blood vessel forms an endothelial lumen through which blood will flow; in vertebrates, the lumen of all blood vessels is lined and formed by endothelial cells; in both vasculogenesis and angiogenesis, lumen formation takes place in a cord of endothelial cells and involves a complex mechanism composed of endothelial cell repulsion at the cell-cell contacts within the endothelial cell cords, junctional rearrangement, and endothelial cell shape change
  • synonyms:
  • abnormal blood vessel lumenization
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Phenotype

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