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MP Term : Lewy bodies [MP:0014065] Mammalian Phenotype

Namespace  MPheno.ontology Obsolete  false
description  Intracytoplasmic eosinophilic neuronal inclusions seen especially in pigmented brainstem neurons and in the cortex; brainstem Lewy bodies consist of a dense core surrounded by a halo of 10-nm-wide radiating fibrils, the primary structural component of which is alpha-synuclein; cortical Lewy bodies are also composed of alpha-synuclein fibrils, but are less defined and lack halos; Lewy bodies are seen in Parkinson disease, Lewy body dementia and other forms of dementia
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Phenotype

Mammalian phenotypes (MP terms) --> Mouse genes and models

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents