|  Help  |  About  |  Contact Us

GO Term : phosphatidylinositol 3-kinase/protein kinase B signal transduction [GO:0043491] Gene Ontology
Namespace  biological_process Obsolete  false
description  An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.
  • synonyms:
  • PKB signal transduction,
  • PKB signalling cascade,
  • AKT signalling cascade,
  • PKB signaling,
  • AKT signaling,
  • protein kinase B signalling cascade,
  • PI3K/Akt signal transduction,
  • PI3K-PKB/Akt pathway,
  • AKT signal transduction,
  • PI3K/PKB signal transduction,
  • protein kinase B signaling,
  • phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction,
  • PKB signaling cascade,
  • protein kinase B signaling cascade,
  • protein kinase B signal transduction,
  • AKT signaling cascade
Paste the following link
Quick Links:
SummaryFunctionOntology
 
Quick Links:
SummaryFunctionOntology
 
Lists
This GOTerm is in one list:
Pax GO Terms 2013-03-14 (239)

Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom