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GO Term : tetrahydrofolylpolyglutamate synthase activity [GO:0004326] Gene Ontology
Namespace  molecular_function Obsolete  false
description  Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).
  • synonyms:
  • tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity,
  • FPGS activity,
  • tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming),
  • folylpoly-gamma-glutamate synthase activity,
  • formyltetrahydropteroyldiglutamate synthetase activity,
  • folylpolyglutamate synthetase activity,
  • N10-formyltetrahydropteroyldiglutamate synthetase activity,
  • tetrahydrofolate synthase activity,
  • tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming),
  • folylpolyglutamyl synthetase activity,
  • folylpoly(gamma-glutamate) synthase activity,
  • folate polyglutamate synthetase activity,
  • folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity,
  • N(10)-formyltetrahydropteroyldiglutamate synthetase activity,
  • folylpolyglutamate synthase activity
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