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GO Term : beta-catenin destruction complex [GO:0030877] Gene Ontology

Namespace

cellular_component

Obsolete

false

description

A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.

synonyms:
23S APC complex,
Axin-APC-beta-catenin-GSK3B complex,
GO:0034747,
APC-Axin-1-beta-catenin complex,
beta-catenin degradation complex,
BDC,
GO:0034742

Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents

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