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GO Term : Fanconi anaemia nuclear complex [GO:0043240] Gene Ontology
Namespace  cellular_component Obsolete  false
description  A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
  • synonyms:
  • FA complex,
  • FA core complex,
  • Fanconi anaemia complex,
  • FA nuclear complex
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