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GO Term : mCRD-mediated mRNA stability complex [GO:0106002] Gene Ontology
Namespace  cellular_component Obsolete  false
description  A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP.
  • synonyms:
  • major coding region instability determinant-poly(A)-bridging complex,
  • major coding region determinant of instability-mediated mRNA stability complex,
  • major coding region instability determinant-mediated mRNA stability complex,
  • major coding-region determinant of instability - poly(A) tail-bridging complex,
  • mCRD-poly(A)-bridging complex
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