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GO Term : 25-hydroxycholesterol 7-alpha-hydroxylase activity [GO:0033783] Gene Ontology

Namespace

molecular_function

Obsolete

false

description

Catalysis of the reactions: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts (25R)-cholest-5-ene-3beta,26-diol to (25R)-cholest-5-en-3beta,7alpha,26-triol.

synonyms:
CYP7B1,
CYP7B1 oxysterol 7alpha-hydroxylase activity,
cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity,
25-hydroxycholesterol 7alpha-monooxygenase activity

Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents

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