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GO Term : PAR polarity complex [GO:0120157] Gene Ontology

Namespace

cellular_component

Obsolete

false

description

A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.

synonyms:
PAR3/PAR6/aPKC,
PAR6-PAR3-aPKC complex,
apical polarity complex,
Cdc42p GEF-PAK complex,
BEM1-CDC24-CLA4 complex,
PAR3-PAR6-atypical PKC

Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents

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