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GO Term : Hrd1p ubiquitin ligase complex [GO:0000836] Gene Ontology
Namespace  cellular_component Obsolete  false
description  A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
  • synonyms:
  • HRD1 ubiquitin ligase complex
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