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Comment :

Type  MGI:General Description  exhibited glomerular lesions of varying degrees at 9 months of age but not at 6 months of age and this pathology at 9 months of age was similar to that seen in 3-4 week old homozygous null mice observed infiltration of inflammatory leukocytes in some glomeruli observed electon-dense mesangial deposits that occluded the capillary lumen, subepithelial and subendothelial deposits along the glomerular basement membrane, and in some older mice, highly organized microtubular deposits in the mesangium