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Comment :

Type  MGI:General Description  at E18.5, a small number of tyrosine hydroxylase (TH)-expressing chromaffin cells are scattered among the enlarged cells of the cortex instead of in the medulla these cells do not express phenylethanolamine N-methyltransferase (PNMT) suggesting that these are noradrenergic chromaffin cells at E13.5 and E15.5, a greatly reduced number of chromaffin cells are present in adrenal glands in mutant embryos