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Comment :

Type  MGI:General Description  low doses of MK212 result in more pronounced hypoactivity than in wild-type mice, and food intake can be decreased by treatment with MK212 or mCPP low doses of SB242084, but not ketanserin or SB204741 (all HTR2C-specific antagonists) induce more hypolocomotion than in wild-type mice that cannot be reverted by treatment with haloperidol (a D2, D3 and D4 dopamine receptor antagonist) or R(+)-SCH23390 (a D1 dopamine receptor antagonist)