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Comment :

Type  MGI:General Description  at E8, 2 of 6 mutant embryos show 2-4 subepidermal blebs flanking the neural tube at E9, a few mutant embryos show blood-filled blebs along the neural tube and head at E14, surviving mutant embryos display bleeding at various locations by E16, survivors exhibit extensive bleeding in the head and along the vertebral column despite bleeding, septation in the heart proceeds normally in at least some of E15 survivors