| Type | MGI:General | Description | much less cushion tissue is distributed in the septum forming region compared to wild-type; the cushion tissues of the aortic valve and AV-valve forming regions are similar or larger in size compared to wild-type by E17.5, retardation of cushion tissue remodeling is evident; in wild-type AV cushions, the mesenchyme developed thick fibrils whereas the nulls had fine meshes of thin fibrils spread throughout the mesenchyme ot the cushion |
