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Comment :

Type  MGI:General Description  after treatment with formalin, homozygous mice display decreased pain-related behavior during the late phase (10-45 minutes after injection), thermal hyperalgesia is less prolonged after treatment with carrageenan or complete Freund's adjuvant and absent after treatment with PGE2 homozygous mice display length, weight, blood chemistry, fertility, lifespan, and thermal and mechanical nociception similar to wild-type