| Type | MGI:General | Description | coenzyme Q (CoQ)-dependent complex I + III activity, normalized to citrate synthase activity, is reduced in the kidney at 4 and 6 months of age, and in the muscle at 6 months of age CoQ-dependent complex I + III activity, normalized to CS activity, is increased in the liver at 4 months of age, but not at 6 months CoQ-depended complex II + III activity, normalized to CS activity, is reduced in the kidney, brain, and liver, and slightly increased in the muscle of 1 month old mutants CoQ-depended complex II + III activity, normalized to CS activity, is reduced in the muscle at 6 months of age cytochrome c oxidase and citrate synthase activities are increased in the liver a 4 months of age citrate synthase activity is decreased in the kidney at 6 months of age |