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Publication : X-linked and autosomal genes controlling mouse alpha-galactosidase expression.

First Author  Lusis AJ Year  1978
Journal  Genetics Volume  88
Issue  2 Pages  327-42
PubMed ID  205481 Mgi Jnum  J:5963
Mgi Id  MGI:54440 Doi  10.1093/genetics/88.2.327
Citation  Lusis AJ, et al. (1978) X-linked and autosomal genes controlling mouse alpha-galactosidase expression. Genetics 88(2):327-42
abstractText  Analysis of F2 and backcross animals has confirmed the X-chromosome linkage of Ags, the structural locus for mouse alpha-galactosidase. The position of Ags has been located in the X chromosome, 9 centimorgans from Mo, and the gene order is centromere-Hq-Bn-Ta-Mo-Ags. A variation in the developmental expression of alpha-galactosidase activity, inherited as an autosomal trait, has been characterized using recombinant inbred lines of mice. Among certain recombinant inbred lines, the variation appears to segregate as a single major locus.
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