First Author | Lusis AJ | Year | 1978 |
Journal | Genetics | Volume | 88 |
Issue | 2 | Pages | 327-42 |
PubMed ID | 205481 | Mgi Jnum | J:5963 |
Mgi Id | MGI:54440 | Doi | 10.1093/genetics/88.2.327 |
Citation | Lusis AJ, et al. (1978) X-linked and autosomal genes controlling mouse alpha-galactosidase expression. Genetics 88(2):327-42 |
abstractText | Analysis of F2 and backcross animals has confirmed the X-chromosome linkage of Ags, the structural locus for mouse alpha-galactosidase. The position of Ags has been located in the X chromosome, 9 centimorgans from Mo, and the gene order is centromere-Hq-Bn-Ta-Mo-Ags. A variation in the developmental expression of alpha-galactosidase activity, inherited as an autosomal trait, has been characterized using recombinant inbred lines of mice. Among certain recombinant inbred lines, the variation appears to segregate as a single major locus. |