| First Author | Apostolopoulos J | Year | 2000 |
| Journal | Immunity | Volume | 12 |
| Issue | 2 | Pages | 223-32 |
| PubMed ID | 10714688 | Mgi Jnum | J:65165 |
| Mgi Id | MGI:1913152 | Doi | 10.1016/s1074-7613(00)80175-2 |
| Citation | Apostolopoulos J, et al. (2000) Ly6d-L, a cell surface ligand for mouse Ly6d. Immunity 12(2):223-32 |
| abstractText | The mouse Ly6 gene family encodes proteins found in lymphocytes and other cells. Some are involved in cell activation; no ligands have been found. A ligand for Ly6d (ThB) was identified on lymphocytes using microspheres loaded with Ly6d and the cDNA isolated from a spleen/thymus library by panning on Ly6d. The Ly6d ligand (Ly6d-L) is a nonglycosylated protein of 9 kDa of broad distribution, rich in cysteine, with no discernable transmembrane sequence. Its N and C termini are on the cell surface, where it associates with a 30 kDa protein. Ly6d-L is homologous with an EGF repeat of Notch. |
