| First Author | Aramaki Y | Year | 2005 |
| Journal | FEBS Lett | Volume | 579 |
| Issue | 17 | Pages | 3731-6 |
| PubMed ID | 15978591 | Mgi Jnum | J:99777 |
| Mgi Id | MGI:3583829 | Doi | 10.1016/j.febslet.2005.05.069 |
| Citation | Aramaki Y, et al. (2005) Direct interaction between metastasis-associated protein 1 and endophilin 3. FEBS Lett 579(17):3731-6 |
| abstractText | The yeast two-hybrid system was used to search for partners of mouse metastasis-associated protein 1 (Mta1). Screening of a cDNA library prepared from mouse embryo yielded positive clones coding for endophilin 3. The site of interaction was suggested to be the SH-3-binding domain of Mta1 and SH-3 domain of endophilin 3. This interaction was confirmed by GST pull-down assay in vitro and immunoprecipitation in vivo. The Mta1 and endophilin 3 transcripts were highly expressed in testis and brain. But, Mta1 localized mainly in nucleus and to a lesser extent in cytoplasm while endophilin 3 localized mainly in cytoplasm. If Mta1 functions in cytoplasm, it might be involved in the regulation of endocytosis mediated by endophilin 3. |
