| First Author | Snyder FF | Year | 1983 |
| Journal | Biochem Genet | Volume | 21 |
| Issue | 3-4 | Pages | 323-32 |
| PubMed ID | 6407470 | Mgi Jnum | J:7090 |
| Mgi Id | MGI:55561 | Doi | 10.1007/BF00499142 |
| Citation | Snyder FF, et al. (1983) Genetic variability of purine nucleoside phosphorylase activity in the mouse: relationship to Np-1 and Np-2. Biochem Genet 21(3-4):323-32 |
| abstractText | A survey of 37 inbred strains for erythrocyte purine nucleoside phosphorylase activity showed a greater than threefold range. Six of these strains had significantly greater activity than the others, and all of the high-activity strains had the Np-2 electrophoretic band. The high-purine nucleoside phosphorylase activity trait corresponding to Np-2 was inherited in an autosomal codominant manner and minor differences were apparent in thermal and kinetic properties between low- and high-activity strains. This work provides further support for there being either two structural loci for purine nucleoside phosphorylase, Np-1 and Np-2, or a regulatory-modifier locus. |
