| First Author | Bayarsaihan D | Year | 2003 |
| Journal | Gene Expr Patterns | Volume | 3 |
| Issue | 5 | Pages | 579-89 |
| PubMed ID | 12971990 | Mgi Jnum | J:85875 |
| Mgi Id | MGI:2677190 | Doi | 10.1016/s1567-133x(03)00118-2 |
| Citation | Bayarsaihan D, et al. (2003) Expression of BEN, a member of TFII-I family of transcription factors, during mouse pre- and postimplantation development. Gene Expr Patterns 3(5):579-89 |
| abstractText | BEN is a member of the TFII-I family of transcription factors, characterized by the presence of multiple helix-loop-helix repeat domains. Our immunohistochemical analysis demonstrated broad and extensive expression of BEN during mouse pre- and postimplantation development, with highest levels occuring during early to midgestation. Maternally expressed BEN is present in both the cytoplasm and nuclei of the zygote; however, it retains a predominantly nuclear localization between the two-cell stage of development and early blastocyst stages. This nuclear expression is observed in most tissues throughout development. Although, it is interesting to note that at E4.5-6.5, during early gastrulation stage, BEN is localized in the cytoplasm. At later stages, BEN retains an extensive expression pattern in a variety of developing systems implicating its involvement in tissue development and organogenesis. |
