First Author | Lukey T | Year | 1985 |
Journal | Biochem Genet | Volume | 23 |
Issue | 3-4 | Pages | 347-56 |
PubMed ID | 3925939 | Mgi Jnum | J:7923 |
Mgi Id | MGI:56392 | Doi | 10.1007/BF00504331 |
Citation | Lukey T, et al. (1985) Purine nucleoside phosphorylase (Np) in the mouse: linkage relationship of Np-2 to esterase-10 (Es-10) and Np-1 on chromosome 14. Biochem Genet 23(3-4):347-56 |
abstractText | An improved method for detecting four Np-1 (purine nucleoside phosphorylase) alleles in mouse erythrocytes by cellulose acetate electrophoresis is described. The previous linkage of Np-1 and Es-10 (esterase-10) was confirmed, with a map distance of 13.0 +/- 2.6 cM. Np-2 was detected by either specific activity assay or starch gel electrophoresis and shown to be linked to Es-10, 15.9 +/- 3.1 cM, on chromosome 14. No recombinants between Np-1 and Np-2 were observed in 52 offspring, indicating either that these loci are either closely associated or that Np-2 represents simply a property of existing allelic products of the Np-1 locus. |