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Publication : Purine nucleoside phosphorylase (Np) in the mouse: linkage relationship of Np-2 to esterase-10 (Es-10) and Np-1 on chromosome 14.

First Author  Lukey T Year  1985
Journal  Biochem Genet Volume  23
Issue  3-4 Pages  347-56
PubMed ID  3925939 Mgi Jnum  J:7923
Mgi Id  MGI:56392 Doi  10.1007/BF00504331
Citation  Lukey T, et al. (1985) Purine nucleoside phosphorylase (Np) in the mouse: linkage relationship of Np-2 to esterase-10 (Es-10) and Np-1 on chromosome 14. Biochem Genet 23(3-4):347-56
abstractText  An improved method for detecting four Np-1 (purine nucleoside phosphorylase) alleles in mouse erythrocytes by cellulose acetate electrophoresis is described. The previous linkage of Np-1 and Es-10 (esterase-10) was confirmed, with a map distance of 13.0 +/- 2.6 cM. Np-2 was detected by either specific activity assay or starch gel electrophoresis and shown to be linked to Es-10, 15.9 +/- 3.1 cM, on chromosome 14. No recombinants between Np-1 and Np-2 were observed in 52 offspring, indicating either that these loci are either closely associated or that Np-2 represents simply a property of existing allelic products of the Np-1 locus.
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