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Publication : Molecular cloning and expression of rat betacellulin cDNA.

First Author  Tada H Year  2000
Journal  Biochim Biophys Acta Volume  1492
Issue  1 Pages  285-8
PubMed ID  11004502 Mgi Jnum  J:63016
Mgi Id  MGI:1860332 Doi  10.1016/s0167-4781(00)00106-8
Citation  Tada H, et al. (2000) Molecular cloning and expression of rat betacellulin cDNA(1). Biochim Biophys Acta 1492(1):285-8
abstractText  The cDNA encoding an entire open reading frame of rat betacellulin has been cloned from rat kidney. Expression of this cDNA in COS7 cells showed a significant amount of mitogenic activity in the culture media. Western blotting of the cell lysates suggested that the membrane-anchored precursor was cleaved to release its ectodomain very efficiently.
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