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Publication : Virtual cloning and physical mapping of a human T-box gene, TBX4.

First Author  Yi CH Year  2000
Journal  Genomics Volume  67
Issue  1 Pages  92-5
PubMed ID  10945475 Mgi Jnum  J:117432
Mgi Id  MGI:3696504 Doi  10.1006/geno.2000.6222
Citation  Yi CH, et al. (2000) Virtual cloning and physical mapping of a human T-box gene, TBX4. Genomics 67(1):92-5
abstractText  The Tbx2/3/4/5 subfamily is one of the largest subgroupings within the T-box gene family, the members of which encode developmentally critical transcription factors. TBX4, a human member of the Tbx2/3/4/5 subfamily, has been identified and characterized from a high-throughput genomic sequence. The genomic organization of TBX4 was elucidated by computational sequence analysis, and the putative cDNA sequence was assembled. The genomic organization of TBX4 is very similar to that of TBX5, as is the situation for TBX2 and TBX3. The physical configuration of the TBX4-TBX2 cluster on human chromosome 17q21-q22 is similar to that of the TBX5-TBX3 cluster on chromosome 12q23-q24. The assembled TBX4 cDNA sequence was searched against the EST databases, and a TBX4 EST was identified.
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