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Comment :

Type  MGI:General Description  10-fold more B cells are found in the thymus compared to controls these B cells consist of a major CD19hi population and a minor CD19lo population with similar populations found in the bone marrow the CD19hi B cell population expresses cell surface markers similar to mature B2 B cells the CD19loB cell population have cell surface markers of pro- and pre- B cells single cell genotyping reveals about 94% of the CD19lo population has cre-mediated deletion of the floxed allele while only 26% of the CD19hi allele had the flox allele deleted