| Type | MGI:General | Description | at E18.5, mutant tibiae are smaller and thinner and consist of calcified cartilage and ALP-positive perichondrium in mutant tibiae, most ALP-positive perichondrial cells have a spindle-shaped cell contour and reduced cytoplasm, the extracellular matrix of which lacks both type I collagen and calcifying matrix vesicles notably, some perichondrial cells at the very middle part of mutant tibiae become flattened; a thin layer of type I collagen-based calcified matrix is found near these cells |
